Author

Claudia Marggraff

Bernhard Nocht Institute for Tropical Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Barbara HoneckeriD· 2 shared Helena FehlingiD· 2 shared Iris BruchhausiD· 2 shared Juliett Anders· 2 shared Annika Bea· 1 shared Balázs HorváthiD· 1 shared Charlotte Sophie HanseniD· 1 shared Hanna Lotter· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

Barbara HoneckerORCID

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2 papers

Recent·Most cited

Distinct temporal patterns of liver immune responses to pathogenic and non-pathogenic Entamoeba histolytica clones

Helena Fehling, Johannes Allweier, Barbara Honecker, Claudia Marggraff, Michel-Ruben Glagowski, Juliett Anders, Hannelore Lotter, Iris Bruchhaus

This study compares immune responses to pathogenic and non-pathogenic E. histolytica clones in mice, finding distinct temporal transcriptomic profiles linked to disease severity.

bioRxiv · May 14, 2026 · PreprintImmunology

Entamoeba histolytica extracellular vesicles drive pro-inflammatory monocyte signaling

Barbara Honecker, Valentin A. Bärreiter, Katharina Höhn, Balázs Horváth, Karel Harant, Nahla Galal Metwally, Claudia Marggraff, Juliett Anders, Stephanie Leyk, Maria del Pilar Martinez Tauler, Annika Bea, Charlotte Sophie Hansen, Helena Fehling, Melanie Lütkemeyer, Stephan Lorenzen, , Iris Bruchhaus

This study shows that extracellular vesicles from Entamoeba histolytica drive pro-inflammatory monocyte signaling, contributing to male-biased immunopathology in amebic liver abscesses.

PLoS neglected tropical diseases · Apr 10, 2025Peer-reviewedImmunology