Spatial epigenomic niches underlie glioblastoma cell state plasticity
Sam Kint, Subhi Talal Younes, Shuozhen Bao, Gretchen Long, David Wouters, Erin L. Stephenson, Xing Lou, Mei Zhong, Di Zhang, Graham Su, Archibald Enninful, Mingyu Yang, Huey‐Miin Chen, Katrina I Ellestad, Colleen Anderson, , Marco Gallo
This study identifies two epigenetically-defined spatial niches in glioblastoma that influence cell state plasticity through local and long-range molecular signals.
bioRxiv · May 9, 2025 · PreprintGenomics