Colleen L. Krall

The intersection of inflammation and DNA damage as a novel axis underlying the pathogenesis of autism spectrum disorders

The paper investigates the molecular link between maternal inflammation and ASD by identifying a shared signature in human neurons exposed to IL-17A, suggesting DNA damage response defects contribute to ASD pathogenesis.

Dynamic Regulation Of The Chromatin Environment By ASH1L Modulates Human Neuronal Structure And Function

This study shows that ASH1L mutations disrupt chromatin regulation, leading to neuronal dysfunction and disease-related gene dysregulation, and identifies potential therapeutic strategies.