Holoprosencephaly and Cyclopia in bmp7b and bmpr1ba Crispant zebrafish
Valentyn Kyrychenko, Philipp Rensinghoff, Johannes Bulk, Constanze Frey, Stephan Heermann
This study uses CRISPR/Cas9 to generate zebrafish models of holoprosencephaly (HPE) by disrupting bmp7b and bmpr1ba, showing HPE and cyclopia phenotypes.
Animal Cells and Systems · Jul 1, 2025Peer-reviewedDevelopmental Biology