Author

Philipp Rensinghoff

University of FreiburgORCID 0009-0000-4140-6814Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 1 Organism:zebrafish· 1

Frequent Co-Authors

Johannes BulkiD· 2 shared Stephan HeermanniD· 2 shared Valentyn KyrychenkoiD· 2 shared Constanze Frey· 1 shared

Activity by Year

2022-2025 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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2 shared papersDevelopmental Biology

Johannes BulkORCID

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2 papers

Recent·Most cited

Developmental BiologyAnimal Cells and SystemsPeer-reviewedJul 1, 2025

Holoprosencephaly and Cyclopia in bmp7b and bmpr1ba Crispant zebrafish

Valentyn Kyrychenko, Philipp Rensinghoff, Johannes Bulk…·Stephan Heermann

This study uses CRISPR/Cas9 to generate zebrafish models of holoprosencephaly (HPE) by disrupting bmp7b and bmpr1ba, showing HPE and cyclopia phenotypes.

1 citation

zebrafishexperimental assay

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Developmental BiologybioRxivPreprintDec 1, 2022

Early eye and forebrain development are facilitated by Bone Morphogenetic Protein antagonism

Johannes Bulk, Valentyn Kyrychenko, Philipp Rensinghoff, Stephan Heermann

The paper investigates the role of BMP antagonists in early eye and forebrain development, finding that BMP ligand overexpression leads to HPE with anophthalmia instead of cyclopia.

DOI 10.1101/2022.12.01.518698

mouseexperimental assay

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