Sensory input drives rapid homeostatic scaling of the axon initial segment in mouse barrel cortex
Nora Jamann, Dominik Dannehl, Nadja Lehmann, Robin Jan Wagener, Corinna Thielemann, Christian Schultz, Jochen F. Staiger, Maarten H. P. Kole, Maren Engelhardt
The paper shows sensory input drives rapid homeostatic scaling of the axon initial segment in mouse barrel cortex, with sensory deprivation increasing AIS length and excitability, while enrichment shortens AIS and reduces action potential generation.
Nature Communications · Jan 4, 2021Peer-reviewedNeuroscience