Prion propagation is dependent on key amino acids in Charge cluster 2 within the prion protein
Savroop K. Bhamra, Parineeta Arora, Szymon W. Manka, Christian Schmidt, Craig A. Brown, Melissa Rayner, Peter‐Christian Klöhn, Anthony R. Clarke, John Collinge, Parmjit Jat
The paper identifies key amino acids in Charge Cluster 2 of the prion protein critical for prion propagation across multiple strains.
Journal of Molecular Biology · Dec 16, 2022Peer-reviewedMolecular Biology