Author

Parmjit Jat

MRC Prion UnitORCID 0000-0002-3354-0594Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Research Focus:protein design· 1 Assay:protein structure· 1

Frequent Co-Authors

Christian SchmidtiD· 2 shared John CollingeiD· 2 shared Melissa RayneriD· 2 shared Parineeta AroraiD· 2 shared Akın NihatiD· 1 shared Anthony R. ClarkeiD· 1 shared Craig A. Brown· 1 shared Jacqueline M. Linehan· 1 shared

Activity by Year

2022-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

Christian SchmidtORCID

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2 papers

Recent·Most cited

NeurosciencebioRxivPreprintNov 23, 2025

A dividing cell model for stable propagation and curing of bona fide human sporadic Creutzfeldt-Jakob Disease prions

Akın Nihat, Parineeta Arora, Christian Schmidt…·Parmjit Jat

This paper introduces a cell-based system for propagating and quantifying human prion infectivity using CAD5 cells expressing human prion protein, demonstrating its effectiveness and therapeutic potential.

1 citation

humanexperimental assay

𝕏 PostBluesky

Molecular BiologyJournal of Molecular BiologyPeer-reviewedDec 16, 2022

Prion propagation is dependent on key amino acids in Charge cluster 2 within the prion protein

Savroop K. Bhamra, Parineeta Arora, Szymon W. Manka…·Parmjit Jat

The paper identifies key amino acids in Charge Cluster 2 of the prion protein critical for prion propagation across multiple strains.

8 citations

mouseprotein structure

𝕏 PostBluesky