Author
Department of Infectious Disease, Imperial College London, London, SW7 2AZ, UK;ORCID 0000-0001-6733-146XUnclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Varun Ramaswamy, Szymon W Manka, Darsh D Sharma…·Carolyn Moores
This study shows that taxane-stabilized microtubules can adopt 15-protofilament structures, which DCX can bind through conformational remodeling, contrasting with the rigid GMPCPP-stabilized lattice.
Savroop K. Bhamra, Parineeta Arora, Szymon W. Manka…·Parmjit Jat
The paper identifies key amino acids in Charge Cluster 2 of the prion protein critical for prion propagation across multiple strains.
Alexander D. Cook, Szymon W. Manka, Su Wang…·Joseph Atherton
The paper presents a pipeline for cryo-EM image processing of microtubules using RELION, enabling accurate determination of microtubule architecture and seam location with near-atomic resolution.