FHOD-1/profilin-mediated actin assembly protects sarcomeres against contraction-induced deformation in C. elegans
Michael J. Kimmich, Sumana Sundaramurthy, Meaghan A. Geary, Leila Lesanpezeshki, Curtis V. Yingling, Siva A. Vanapalli, Ryan S. Littlefield, David Pruyne
This study shows FHOD-1 and profilin cooperate to stabilize sarcomere Z-lines in C. elegans by promoting actin assembly and preventing muscle deformation during contraction.
Molecular Biology of the Cell · Sep 11, 2024Peer-reviewedCell Biology