David Mazaud

The paper identifies SYBU as a regulator of mitochondrial transport in breast cancer cells, showing that its loss leads to increased migration via a feedback loop involving microtubule deacetylation and kinesin-1 activity.

The paper shows H3.3 deposition counteracts H3.1 enrichment at chromocenters in ESCs, affecting heterochromatin stability and cell survival.

This study shows that astroglial Ophn1 deficiency impairs synaptic transmission and behavior, with potential therapeutic targeting of the RhoA/ROCK pathway.

This study links proteotoxic stress from defective autophagy to epileptogenesis in Drosophila and Vici Syndrome patients, suggesting autophagy-stimulating diets as a potential treatment.

This study identifies Dia2 as a regulator of lipid nanodomain organization at the plasma membrane, impacting JAK/STAT signaling and membrane protein activity.

The paper investigates region-specific properties of astrocytes in the visual layer of the superior colliculus, finding they have higher density, complex morphology, and closer proximity to synapses compared to astrocytes in other brain regions.

The paper shows dendritic spines refill ER calcium stores through controlled calcium entry without depletion, using computational modeling and imaging.

The paper identifies a unique molecular repertoire in hippocampal perisynaptic astrocytic processes, regulated by local translation during fear conditioning.