Phenotypical microRNA screen reveals a noncanonical role of CDK2 in regulating neutrophil migration
A. Y. Hsu, D. Wang, S. Liu, J. Lu, R. S. Sobreira, D. A. Bennin, A. Huttenlocher, D. M. Umulis, J. Wan, Q. Deng
The paper identifies miR-199 as a suppressor of neutrophil migration and inflammation by targeting CDK2, revealing a noncanonical role for CDK2 in cell polarity and chemotaxis.
bioRxiv · Mar 20, 2019Immunology