Extracellular vimentin as a target against SARS- CoV-2 host cell invasion
L. Suprewicz, M. Swoger, S. Gupta, E. Piktel, F. F. Byfield, D. V. Iwamoto, D. A. Germann, J. Reszec, N. Marcinczyk, R. Carroll, M. Lenart, K. Pyrc, P. A. Janmey, J. M. Schwarz, R. Bucki, A. E. Patteson
The paper identifies extracellular vimentin as a potential target for preventing SARS-CoV-2 infection by showing it facilitates viral entry through interaction with the spike protein and ACE2.
bioRxiv · Jan 8, 2021Biophysics