Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator
M. Sone, N. Mitsuhashi, Y. Sugiura, Y. Matsuoka, R. Maeda, A. Yamauchi, R. Okahashi, J. Yamashita, K. Sone, S. Enju, D. Anegawa, Y. Yamaguchi
This study identifies Gpx4 and ferroptosis-suppressing pathways as key to cold resistance in hibernator cells, showing their potential to enhance cold tolerance in non-hibernators.
bioRxiv · Dec 27, 2023Cell Biology