Author

Y. Sugiura

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 5 Physiology· 2 Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Organism:mouse· 5 Assay:bulk RNA-seq· 3 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:metabolism & bioenergetics· 3 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2

Frequent Co-Authors

M. Suematsu· 4 shared M. Yamamoto· 2 shared Y. Tanaka· 2 shared A. Iwama· 1 shared A. Nakamura-Ishizu· 1 shared A. Nishiyama· 1 shared A. Okada· 1 shared A. Yamauchi· 1 shared

Activity by Year

2020-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersCell Biology

M. Suematsu

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Identification of genes supporting cold resistance of mammalian cells: lessons from a hibernator

M. Sone, N. Mitsuhashi, Y. Sugiura, Y. Matsuoka, R. Maeda, A. Yamauchi, R. Okahashi, J. Yamashita, K. Sone, S. Enju, D. Anegawa, Y. Yamaguchi

This study identifies Gpx4 and ferroptosis-suppressing pathways as key to cold resistance in hibernator cells, showing their potential to enhance cold tolerance in non-hibernators.

bioRxiv · Dec 27, 2023Cell Biology

Context-Dependent Modification of PFKFB3 in Hematopoietic Stem Cells Promotes Anaerobic Glycolysis and Ensures Stress Hematopoiesis

S. Watanuki, H. Kobayashi, Y. Sugiura, M. Yamamoto, D. Karigane, K. Shiroshita, Y. Sorimachi, S. Fujita, T. Morikawa, S. Koide, M. Oshima, A. Nishiyama, K. Murakami, H. Miho, S. Tamaki, , K. Takubo

This study identifies PFKFB3 as a key regulator of glycolytic metabolism in HSCs under stress, showing its context-dependent activation promotes ATP production and hematopoiesis.

bioRxiv · Mar 16, 2023Cell Biology

Cardiomyocyte transcriptomic signatures in response to Trypanosoma cruzi infection underpin Chagas cardiomyopathy progression.

K. Candray, Y. Nakagama, I. Masamichi, S. Nakagama, E. Tshibangu-Kabamba, N. Takeda, Y. Sugiura, Y. Nitahara, Y. Michimuko-Nagahara, N. Kaku, Y. Onizuka, C.-E. Arias, M. Mejia, K. Alas, S. Pena, , Y. Kido

This study identifies transcriptomic changes in cardiomyocytes infected with different T. cruzi strains, highlighting pathways linked to Chagas cardiomyopathy progression.

bioRxiv · Feb 27, 2023 · PreprintCell Biology

Quantitative analysis of calcium oxalate monohydrate and dihydrate for elucidating the formation mechanism of calcium oxalate kidney stones

M. Maruyama, K. P. Sawada, Y. Tanaka, A. Okada, K. Momma, M. Nakamura, R. Mori, Y. Furukawa, Y. Sugiura, R. Tajiri, K. Taguchi, S. Hamamoto, R. Ando, K. Tsukamoto, K. Takano, , Y. Mori

This paper quantitatively analyzes calcium oxalate monohydrate and dihydrate in kidney stones using FTIR, PXRD, and micro-CT to understand their formation mechanisms.

bioRxiv · Oct 20, 2022Biophysics

DNA damage response signaling to mitochondria drives senescence

S. Yamauchi, Y. Sugiura, J. Yamaguchi, X. Zhou, T. Odawara, S. Fukaya, I. Naguro, Y. Uchiyama, H. Ichijo

This study identifies BNIP3 as a mediator of DNA damage response signaling to mitochondria, which promotes senescence by altering mitochondrial structure and metabolism to increase p16 expression.

bioRxiv · Sep 22, 2022Cell Biology

Myristate can be used as a carbon and energy source for the asymbiotic growth of arbuscular mycorrhizal fungi

Y. Sugiura, R. Akiyama, S. Tanaka, K. Yano, H. Kameoka, S. Marui, M. Saito, M. Kawaguchi, K. Akiyama, K. Saito

This study shows that myristate supports asymbiotic growth of arbuscular mycorrhizal fungi by serving as a carbon and energy source.

bioRxiv · Sep 3, 2020Microbiology

Senescent cell death as an aging resistance mechanism in naked mole-rat

Y. Kawamura, K. Oka, M. Takamori, Y. Sugiura, Y. Oiwa, S. Fujioka, S. Homma, S. Miyawaki, M. Narita, T. Fukuda, M. Suematsu, H. Bono, H. Okano, K. Miura

This study identifies senescent cell death as a mechanism contributing to the aging resistance in naked mole-rats, linking low antioxidant defense with suppressed senescent cell accumulation.

bioRxiv · Jul 2, 2020Cell Biology

Visualizing ATP Dynamics in Live Mice

N. Koitabashi, R. Ogasawara, R. Yasui, Y. Sugiura, H. Matsuda, S. Nonaka, T. Izumi, M. Kurabayashi, M. Suematsu, M. Yanagita, H. Imamura, M. Yamamoto

The paper develops a transgenic mouse model with GO-ATeam to measure ATP dynamics in real-time across multiple organs and conditions, providing insights into ATP's role in physiology and disease.

bioRxiv · Jun 10, 2020 · PreprintPhysiology

Prostaglandin in the ventromedial hypothalamus regulates peripheral glucose metabolism

M.-L. Lee, H. Matsunaga, Y. Sugiura, T. Hayasaka, I. Yamamoto, D. Imoto, M. Suematsu, N. Iijima, K. Kimura, S. Diano, C. Toda

This study shows that cPLA2-mediated phospholipid metabolism in the VMH regulates glucose metabolism under RCD but worsens it under HFD through changes in insulin sensitivity and inflammation.

bioRxiv · May 18, 2020Physiology