IRES-independent, eIF2A/eIF2D-dependent translation of the enterovirus genome
H. Kim, D. Aponte-Diaz, M. S. Sotoudegan, J. J. Arnold, C. E. Cameron
This study shows that enterovirus genome recombination depends on eIF2A/eIF2D-dependent translation, not IRES-mediated translation, and explains non-replicative recombination and RNA persistence.
bioRxiv · Jun 1, 2022Microbiology