Measuring nucleus mechanics within a living multicellular organism: Physical decoupling and attenuated recovery rate are physiological protective mechanisms of the cell nucleus under high mechanical load
N. Zuela-Sopilniak, D. Bar-Sela, C. Charar, O. Wintner, Y. Gruenbaum, A. Buxboim
The paper measures nucleus mechanics in living C. elegans, finding non-monotonic deformation and viscoelastic decoupling under stress, which protect nuclear integrity.
bioRxiv · Feb 5, 2020Cell Biology