Author

Y. Gruenbaum

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:C. elegans· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:metabolism & bioenergetics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:human· 1

Frequent Co-Authors

C. Charar· 2 shared A. Buxboim· 1 shared A. Florwick· 1 shared A. Wriston· 1 shared C. R. Carlson· 1 shared D. Bar-Sela· 1 shared D. F. Hunt· 1 shared D. N. Simon· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

C. Charar

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Author profile →

3 papers

Recent·Most cited

Lamin regulates the dietary restriction response via the mTOR pathway in Caenorhabditis elegans

C. Charar, S. Metsuyanim-Cohen, Y. Gruenbaum, D. Z. Bar

This study shows that lamin regulates dietary restriction response in C. elegans by modulating the mTOR pathway through nuclear localization of RAGC-1.

bioRxiv · Oct 27, 2020Cell Biology

Measuring nucleus mechanics within a living multicellular organism: Physical decoupling and attenuated recovery rate are physiological protective mechanisms of the cell nucleus under high mechanical load

N. Zuela-Sopilniak, D. Bar-Sela, C. Charar, O. Wintner, Y. Gruenbaum, A. Buxboim

The paper measures nucleus mechanics in living C. elegans, finding non-monotonic deformation and viscoelastic decoupling under stress, which protect nuclear integrity.

bioRxiv · Feb 5, 2020Cell Biology

OGT (O-GlcNAc Transferase) selectively modifies multiple residues unique to lamin A

D. N. Simon, A. Wriston, Q. Fan, J. Shabanowitz, A. Florwick, T. Dharmaraj, S. B. Peterson, Y. Gruenbaum, C. R. Carlson, L. M. Gronning-Wang, D. F. Hunt, K. L. Wilson

This study identifies O-GlcNAc modifications unique to lamin A, showing OGT modifies specific residues in lamin A tails but not lamin B1, lamin C, or progerin.

bioRxiv · Oct 26, 2017Biochemistry