Author

D. C. Avgousti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:electronic health records· 1

Frequent Co-Authors

E. A. Arnold· 2 shared H. C. Lewis· 2 shared L. E. Kelnhofer-Millevolte· 2 shared M. R. Brinkley· 2 shared H. E. Arbach· 1 shared K. L. Lynch· 1 shared K. Leung· 1 shared M. Bat-Erdene· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersMicrobiology

E. A. Arnold

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Adenovirus protein VII binds the A-box of HMGB1 to repress interferon responses.

E. A. Arnold, R. J. Kaai, K. Leung, M. R. Brinkley, L. E. Kelnhofer-Millevolte, M. S. Guo, D. C. Avgousti

This study shows adenovirus protein VII binds HMGB1's A-box to sequester it in chromatin, inhibiting interferon β expression but not downstream interferon-stimulated genes.

bioRxiv · Apr 17, 2023 · PreprintMicrobiology

HSV-1 exploits host heterochromatin for egress

H. C. Lewis, L. E. Kelnhofer-Millevolte, M. R. Brinkley, H. E. Arbach, E. A. Arnold, S. Ramachandran, D. C. Avgousti

This study shows HSV-1 uses host heterochromatin for viral egress, with loss of H3K27me3 or macroH2A1 causing capsid trapping.

bioRxiv · May 31, 2022 · PreprintMicrobiology

A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle

K. L. Lynch, M. Bat-Erdene, M. R. Dillon, H. C. Lewis, D. C. Avgousti

This study shows adenovirus protein VII disrupts the H1-HMGB balance to block the cell cycle, ensuring resources for viral replication.

bioRxiv · Dec 11, 2020Microbiology