Enhancing top-down proteomics of brain tissue with FAIMS
J. M. Fulcher, A. Makaju, R. J. Moore, M. Zhou, D. C. Bennett, P. L. De Jager, W.-J. Qian, L. Pasa-Tolic, V. A. Petyuk
This study shows that adding FAIMS to top-down proteomics improves proteome coverage in Alzheimer's brain tissue by doubling the number of non-redundant proteoforms identified.
bioRxiv · Jan 18, 2021Biochemistry