D. C. K. Chan

Nutrient Limitation Sensitizes Pseudomonas aeruginosa to Vancomycin

This study shows that vancomycin inhibits Pseudomonas aeruginosa growth under nutrient limitation and identifies resistance mechanisms linked to LPS biosynthesis and CpxSR signaling.

A single extracellular loop of FoxA controls ligand specificity, uptake, and signaling in Pseudomonas aeruginosa

The paper shows that a single extracellular loop of FoxA controls ligand specificity, uptake, and signaling in Pseudomonas aeruginosa by affecting different siderophores.

Pseudomonas aeruginosa FpvB is a high-affinity transporter for xenosiderophores ferrichrome and ferrioxamine B

The paper identifies FpvB as a high-affinity transporter for xenosiderophores ferrichrome and ferrioxamine B in Pseudomonas aeruginosa, revealing its role in antibiotic uptake and transport promiscuity.

Thiocillin and Micrococcin Exploit the Ferrioxamine Receptor of Pseudomonas aeruginosa for Uptake

The paper identifies that thiocillin and micrococcin use the ferrioxamine receptor FoxA to enter Pseudomonas aeruginosa, enhancing their antibacterial activity under iron-limiting conditions.

Forging new antibiotic combinations under iron-limiting conditions

The paper identifies antibiotic combinations that synergize with thiostrepton to combat multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii under iron-limiting conditions.

Thiostrepton hijacks pyoverdine receptors to inhibit growth of Pseudomonas aeruginosa

This paper identifies thiostrepton's activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii under iron-limited conditions by exploiting pyoverdine receptors.