Author

L. N. Yaeger

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:bacteria (other)· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

L. L. Burrows· 4 shared H. Harvey· 3 shared J. Chee· 2 shared J.-P. Cote· 2 shared M. R. M. Ranieri· 2 shared M. Rudolph· 2 shared A. Dobrin· 1 shared A. Giovannoni· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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4 shared papersMicrobiology

L. L. Burrows

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4 papers

Recent·Most cited

Metabolic connections between folate and peptidoglycan pathways in Pseudomonas aeruginosa inform rational design of a dual-action inhibitor

L. N. Yaeger, D. Sycantha, P. Luong, S. Shekarriz, O. Goncalves, A. Dobrin, M. R. Ranieri, R. P. Lamers, H. Harvey, G. C. diCenzo, M. G. Surette, J.-P. Cote, J. Magolan, L. L. Burrows

This study identifies metabolic links between folate and peptidoglycan pathways in Pseudomonas aeruginosa and uses these insights to design a dual-action inhibitor that overcomes antibiotic resistance.

bioRxiv · Nov 22, 2023 · PreprintMicrobiology

A genetic screen identifies a role for oprF in Pseudomonas aeruginosa biofilm stimulation by subinhibitory antibiotics

L. N. Yaeger, M. R. M. Ranieri, J. Chee, S. Karabelas-Pittman, M. Rudolph, A. Giovannoni, H. Harvey, L. L. Burrows

This paper identifies OprF and SigX as key factors in sub-MIC antibiotic-induced biofilm formation in Pseudomonas aeruginosa, linking periplasmic redox changes to c-di-GMP signaling.

bioRxiv · Sep 5, 2023 · PreprintMicrobiology

Central metabolism is a key player in E. coli biofilm stimulation by sub-MIC antibiotics

L. N. Yaeger, S. French, E. D. Brown, J.-P. Cote, L. L. Burrows

This study identifies central metabolism and respiration as key drivers of E. coli biofilm formation in response to sub-MIC antibiotics.

bioRxiv · Sep 14, 2022Microbiology

Thiostrepton hijacks pyoverdine receptors to inhibit growth of Pseudomonas aeruginosa

M. R. M. Ranieri, D. C. K. Chan, L. N. Yaeger, M. Rudolph, S. Kerabalas-Pittman, H. Abdo, J. Chee, H. Harvey, U. Nguyen, L. L. Burrows

This paper identifies thiostrepton's activity against multidrug-resistant Pseudomonas aeruginosa and Acinetobacter baumannii under iron-limited conditions by exploiting pyoverdine receptors.

bioRxiv · Mar 5, 2019Microbiology