D. C. RAMIREZ

VITAMIN A DEFICIENCY CAUSES APOPTOSIS IN THE MAMMARY GLAND OF RATS

This study shows that vitamin A deficiency in rats leads to mammary gland dysfunction through increased inflammation, apoptosis, and reduced cell proliferation, which can be reversed with a vitamin A sufficient diet.

Trapping DNA-radicals with DMPO reduced hypochlorous acid-induced 8-oxo-7,8-dihydro-2'-deoxyguanosine and mutagenesis in lung epithelial cells

This paper investigates how DMPO traps DNA-centered radicals induced by HOCl, reducing 8-oxo-dGuo formation and mutagenesis in lung epithelial cells exposed to neutrophilic inflammation.

Exotoxins secreted by Clostridium septicum induce macrophage death: implications for bacterial immune evasion mechanisms at infection sites

This study shows that exotoxins from Clostridium septicum induce macrophage death via autophagy-triggered apoptosis, aiding bacterial immune evasion.

Drugs targeting microRNAs that regulate DNA damage sensing and repair mechanisms: A computational drug discovery approach

The paper uses computational methods to identify drugs that target miRs regulating DNA damage sensing and repair, finding five compounds that could downregulate these miRs.