Author

D. Croote

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Research Focus:clustering· 3 Organism:human· 3 Assay:scRNA-seq· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

S. R. Quake· 3 shared A. M. Sanz· 2 shared F. Zanini· 2 shared L. L. Albornoz· 2 shared M. Robinson· 2 shared S. Einav· 2 shared A. Agrawal· 1 shared B. A. Pinsky· 1 shared

Activity by Year

2017-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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3 shared papersImmunology

S. R. Quake

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Author profile →

4 papers

Recent·Most cited

Functional characterization and lineage analysis of broadly neutralizing human antibodies against dengue virus identified by single B cell transcriptomics

N. D. Durham, A. Agrawal, E. Waltari, D. Croote, F. Zanini, M. Fouch, E. Davidson, O. Smith, E. Carabajal, J. E. Pak, B. J. Doranz, M. Robinson, A. M. Sanz, L. L. Albornoz, F. Rosso, , L. Goo

The paper identifies two broadly neutralizing antibodies against dengue virus through single B cell transcriptomics and characterizes their epitopes and evolutionary pathways.

bioRxiv · Oct 2, 2019Microbiology

Virus-inclusive single cell RNA sequencing reveals molecular signature predictive of progression to severe dengue infection

F. Zanini, M. Robinson, D. Croote, M. K. Sahoo, A. M. Sanz, E. Ortiz-Lasso, L. L. Albornoz, F. R. Suarez, J. G. Montoya, B. A. Pinsky, S. Quake, S. Einav

This study uses single-cell RNA sequencing to identify molecular signatures predictive of severe dengue infection by analyzing PBMCs from dengue patients and healthy controls.

bioRxiv · Aug 9, 2018Immunology

Human IgE producing B cells have a unique transcriptional program and generate high affinity, allergen-specific antibodies

D. Croote, S. Darmanis, K. C. Nadeau, S. R. Quake

The paper isolates and characterizes IgE-producing B cells from allergic individuals using scRNA-seq, revealing unique transcriptional features, high-affinity antibodies, and convergent evolution in allergen specificity.

bioRxiv · May 22, 2018Immunology

Matrix-corrected mass spectrometry enables sensitive detection of food allergens and reveals widespread soy contamination of processed foods

D. Croote, I. Braslavsky, S. R. Quake

The paper develops a mass spectrometry method to detect food allergens and finds widespread soy contamination in processed foods, with many precautionary labels not accurately reflecting contamination risks.

bioRxiv · Dec 12, 2017Immunology