Author

M. K. Sahoo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Organism:human· 6 Research Focus:cell type annotation· 3 Research Focus:cell-cell communication· 3 Research Focus:differential expression· 3 Assay:proteomics· 3 Research Focus:host-pathogen & immune response· 2 Assay:scRNA-seq· 2

Frequent Co-Authors

B. A. Pinsky· 7 shared S. Einav· 4 shared A. M. Sanz· 3 shared J. G. Montoya· 3 shared F. Rosso· 2 shared F. Zanini· 2 shared L. Ghita· 2 shared M. Robinson· 2 shared

Activity by Year

2018-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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7 shared papersImmunology

B. A. Pinsky

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

XBB.1.5 monovalent booster improves antibody binding and neutralization against emerging SARS-CoV-2 Omicron variants

S. Jain, S. Kumar, L. Lai, S. Linderman, A. A. Malik, M. L. Ellis, S. Godbole, D. Solis, M. K. Sahoo, K. Bechnak, I. Paredes, R. Tanios, B. Kazzi, S. M. Dib, M. B. Litvack, , M. S. Suthar

The paper evaluates the effectiveness of an XBB.1.5 monovalent booster vaccine, showing improved antibody binding and neutralization against SARS-CoV-2 Omicron variants.

bioRxiv · Feb 3, 2024 · PreprintImmunology

Global and cell type-specific immunological hallmarks of severe dengue progression

L. Ghita, Z. Yao, Y. Xie, V. Duran, B. H. Cagirici, J. Samir, I. Osman, O. L. Agudelo, A. M. Sanz, M. K. Sahoo, M. Robinson, R. M. Gelvez, N. Bueno, F. Luciani, B. A. Pinsky, , S. Einav

This study identifies DENV target cells and immunological changes in severe dengue progression using single-cell RNA-Seq and functional assays in children.

bioRxiv · Dec 11, 2022 · PreprintImmunology

Magnitude and kinetics of the human immune cell response associated with severe dengue progression by single-cell proteomics

M. L. Robinson, D. R. Glass, V. Duran, O. Rojas, A. M. Sanz, M. Consuegra, M. K. Sahoo, F. Hartmann, M. Bosse, R. M. G. Ramirez, N. Bueno, B. A. Pinsky, J. G. Montoya, H. Maecker, M. Cardenas, , S. Einav

The paper uses single-cell proteomics to analyze immune cell responses in severe dengue patients, identifying distinct immune dynamics compared to uncomplicated dengue.

bioRxiv · Sep 21, 2022Immunology

Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for therapy

M. Karim, S. Saul, L. Ghita, M. K. Sahoo, C. Ye, N. Bhalla, J. Jin, J.-G. Park, B. Martinez-Gualda, M. Patrick East, G. L. Johnson, B. A. Pinsky, L. Martinez-Sobrido, C. R. M. Asquith, A. Narayanan, , S. Einav

This study shows that Numb-associated kinases are essential for SARS-CoV-2 infection and that inhibiting them can suppress viral infection in human lung cells.

bioRxiv · Mar 18, 2022 · PreprintMicrobiology

Electric-field-driven microfluidics for rapid CRISPR-based diagnostics and its application to detection of SARS-CoV-2

A. Ramachandran, D. A. Huyke, E. Sharma, M. K. Sahoo, N. Banaei, B. A. Pinsky, J. G. Santiago

This paper develops an electric-field-driven microfluidic system for CRISPR-based diagnostics, achieving SARS-CoV-2 detection in 30 minutes from raw sample to result.

bioRxiv · May 21, 2020Bioengineering

Comparison of the Accula SARS-CoV-2 Test with a Laboratory-Developed Assay for Detection of SARS-CoV-2 RNA in Clinical Nasopharyngeal Specimens

C. A. Hogan, N. Garamani, A. S. Lee, J. K. Tung, M. K. Sahoo, C. Huang, B. Stevens, J. Zehnder, B. A. Pinsky

This study compares the Accula SARS-CoV-2 POC test with a lab-developed assay, finding high negative agreement but lower positive agreement for low viral load samples.

bioRxiv · May 12, 2020Microbiology

Virus-inclusive single cell RNA sequencing reveals molecular signature predictive of progression to severe dengue infection

F. Zanini, M. Robinson, D. Croote, M. K. Sahoo, A. M. Sanz, E. Ortiz-Lasso, L. L. Albornoz, F. R. Suarez, J. G. Montoya, B. A. Pinsky, S. Quake, S. Einav

This study uses single-cell RNA sequencing to identify molecular signatures predictive of severe dengue infection by analyzing PBMCs from dengue patients and healthy controls.

bioRxiv · Aug 9, 2018Immunology