Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
15 papers
Recent·Most cited
M. Karim, M. Mishra, C.-W. Lo, S. Saul, H. B. Cagirici, D. H. Nhu Tran, A. Agrawal, L. Ghita, A. Ojha, M. P. East, K. Anbro Gammeltoft, M. Kumar Sahoo, G. L. Johnson, S. Das, D. Jochmans, , S. Einav
RMC-113 inhibits PIP4K2C and PIKfyve, reversing SARS-CoV-2-induced autophagic flux impairment and showing antiviral effects.
bioRxiv · Apr 15, 2024Microbiology
S. Jain, S. Kumar, L. Lai, S. Linderman, A. A. Malik, M. L. Ellis, S. Godbole, D. Solis, M. K. Sahoo, K. Bechnak, I. Paredes, R. Tanios, B. Kazzi, S. M. Dib, M. B. Litvack, , M. S. Suthar
The paper evaluates the effectiveness of an XBB.1.5 monovalent booster vaccine, showing improved antibody binding and neutralization against SARS-CoV-2 Omicron variants.
bioRxiv · Feb 3, 2024 · PreprintImmunology
S. Yoon, E. U. Anaya, J. Sachithanandham, B. A. Pinsky, D. J. Sullivan, H. H. Mostafa, A. Pekosz
This study shows A-lineage SARS-CoV-2 variants evolved mutations similar to B-lineage VOCs, improving replication in human nasal cells and showing temperature-dependent growth advantages.
bioRxiv · Mar 3, 2023 · PreprintMicrobiology
L. Ghita, Z. Yao, Y. Xie, V. Duran, B. H. Cagirici, J. Samir, I. Osman, O. L. Agudelo, A. M. Sanz, M. K. Sahoo, M. Robinson, R. M. Gelvez, N. Bueno, F. Luciani, B. A. Pinsky, , S. Einav
This study identifies DENV target cells and immunological changes in severe dengue progression using single-cell RNA-Seq and functional assays in children.
bioRxiv · Dec 11, 2022 · PreprintImmunology
M. E. Davis-Gardner, L. Lai, B. Wali, H. Samaha, D. Solis, M. Lee, A. Porter-Morrison, I. T. Hentenaar, F. Yamamoto, S. Godbole, D. C. Douek, F. E.-H. Lee, N. Rouphael, A. Moreno, B. A. Pinsky, M. S. Suthar
This study evaluates the neutralizing efficacy of bivalent mRNA boosters against emerging SARS-CoV-2 subvariants BA.2.75.2 and BQ.1.1, showing improved protection compared to monovalent boosters.
bioRxiv · Oct 31, 2022 · PreprintImmunology
M. L. Robinson, D. R. Glass, V. Duran, O. Rojas, A. M. Sanz, M. Consuegra, M. K. Sahoo, F. Hartmann, M. Bosse, R. M. G. Ramirez, N. Bueno, B. A. Pinsky, J. G. Montoya, H. Maecker, M. Cardenas, , S. Einav
The paper uses single-cell proteomics to analyze immune cell responses in severe dengue patients, identifying distinct immune dynamics compared to uncomplicated dengue.
bioRxiv · Sep 21, 2022Immunology
M. E. Zaslavsky, E. Craig, J. K. Michuda, N. Sehgal, N. Ram-Mohan, J.-Y. Lee, K. D. Nguyen, R. A. Hoh, T. D. Pham, K. Röltgen, B. Lam, E. S. Parsons, S. R. Macwana, W. DeJager, E. M. Drapeau, , S. D. Boyd
The paper develops Mal-ID, a machine learning framework using immune receptor data to diagnose diseases, detecting infections, autoimmune disorders, and vaccine responses.
bioRxiv · Apr 26, 2022Immunology
M. Karim, S. Saul, L. Ghita, M. K. Sahoo, C. Ye, N. Bhalla, J. Jin, J.-G. Park, B. Martinez-Gualda, M. Patrick East, G. L. Johnson, B. A. Pinsky, L. Martinez-Sobrido, C. R. M. Asquith, A. Narayanan, , S. Einav
This study shows that Numb-associated kinases are essential for SARS-CoV-2 infection and that inhibiting them can suppress viral infection in human lung cells.
bioRxiv · Mar 18, 2022 · PreprintMicrobiology
C. Zhu, J. Y. Lee, J. Z. Woo, L. Xu, X. Nguyenla, L. H. Yamashiro, F. Ji, S. B. Biering, E. V. Dis, F. Gonzalez, D. Fox, A. Rustagi, B. A. Pinsky, C. A. Blish, C. Chiu, , A. M. Näär
This paper develops an intranasal ASO therapy targeting SARS-CoV-2 RNA that effectively prevents viral replication in multiple models and variants.
bioRxiv · May 17, 2021Microbiology
S. Saul, M. Karim, P.-T. Huang, L. Ghita, W. Chiu, S. Kumar, N. Bhalla, P. Leyssen, C. A. Cohen, K. E. Huie, C. Tindle, M. Sibai, B. A. Pinsky, S. Das, P. Ghosh, , S. Einav
This study identifies lapatinib, an ErbB inhibitor, as a broad-spectrum antiviral that suppresses SARS-CoV-2 and VEEV replication, inflammation, and lung injury through ErbB-mediated mechanisms.
bioRxiv · May 15, 2021Microbiology
V.-V. Edara, L. Lai, M. Sahoo, K. Floyd, M. Sibai, D. Solis, M. W. Flowers, L. Hussaini, C. R. Ciric, S. Bechnack, K. Stephens, E. B. Mokhtari, P. Mudvari, A. Creanga, A. Pegu, , M. Suthar
This study assesses neutralizing antibody responses to the SARS-CoV-2 B.1.617.1 variant in convalescent and vaccinated individuals, finding it is 6.8-fold more resistant but still neutralizable.
bioRxiv · May 9, 2021 · PreprintImmunology
D. Feyaerts, J. Hedou, J. Gillard, H. Chen, E. S. Tsai, L. S. Peterson, K. Ando, M. Manohar, E. Do, G. K. R. Dhondalay, J. Fitzpatrick, M. Artandi, I. Chang, T. T. Snow, R. S. Chinthrajah, , D. R. McIlwain
This study integrates plasma proteomics and single-cell immune features to classify COVID-19 severity and identify biological signatures of disease progression.
bioRxiv · Feb 9, 2021Immunology
A. Ramachandran, D. A. Huyke, E. Sharma, M. K. Sahoo, N. Banaei, B. A. Pinsky, J. G. Santiago
This paper develops an electric-field-driven microfluidic system for CRISPR-based diagnostics, achieving SARS-CoV-2 detection in 30 minutes from raw sample to result.
bioRxiv · May 21, 2020Bioengineering
C. A. Hogan, N. Garamani, A. S. Lee, J. K. Tung, M. K. Sahoo, C. Huang, B. Stevens, J. Zehnder, B. A. Pinsky
This study compares the Accula SARS-CoV-2 POC test with a lab-developed assay, finding high negative agreement but lower positive agreement for low viral load samples.
bioRxiv · May 12, 2020Microbiology
F. Zanini, M. Robinson, D. Croote, M. K. Sahoo, A. M. Sanz, E. Ortiz-Lasso, L. L. Albornoz, F. R. Suarez, J. G. Montoya, B. A. Pinsky, S. Quake, S. Einav
This study uses single-cell RNA sequencing to identify molecular signatures predictive of severe dengue infection by analyzing PBMCs from dengue patients and healthy controls.
bioRxiv · Aug 9, 2018Immunology