Author

N. Hanrahan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Biophysics· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 2 Organism:Arabidopsis· 1 Organism:bacteria (other)· 1 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

S. Mahajan· 3 shared G. Devitt· 2 shared J. West· 2 shared P. B. Johnson· 2 shared R. Forster· 2 shared S. I. R. Lane· 2 shared A. Clooney· 1 shared A. Lister· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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3 shared papersMicrobiology

S. Mahajan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Droplet microfluidics for time-resolved serial crystallography

J. Stubbs, T. Hornsey, N. Hanrahan, L. Blay-Esteban, R. Bolton, M. Maly, S. Basu, J. Orlans, D. de Sanctis, J.-u. Shim, P. D. Shaw Stewart, A. M. Orville, I. Tews, J. West

This paper develops a droplet microfluidics approach to produce uniform crystals and enable rapid micromixing for time-resolved serial crystallography.

bioRxiv · Jan 12, 2024Biochemistry

Mechanisms of SARS-CoV-2 Inactivation using UVC Laser Radiation

G. Devitt, P. B. Johnson, N. Hanrahan, S. I. R. Lane, M. C. Vidale, B. Sheth, J. D. Allen, M. V. Humbert, C. M. Spalluto, R. C. Herve, K. Staples, J. West, R. Forster, N. Divecha, C. J. McCormick, , S. Mahajan

This study investigates the inactivation of SARS-CoV-2 using UVC laser radiation and identifies mechanisms involving RNA damage and disruption of spike protein function.

bioRxiv · Feb 3, 2023Microbiology

An IBD-associated pathobiont synergises with NSAID to promote colitis which is blocked by NLRP3 inflammasome and Caspase-8 inhibitors

R. Singh, V. Rossini, S. R. Stockdale, G. Saiz-Gonzalo, N. Hanrahan, T. D' Souza, A. Clooney, L. A. Draper, C. Hill, K. Nally, F. Shanahan, S. Andersson-Engels, S. Melgar

The paper shows that AIEC synergizes with NSAID to worsen colitis in IL10 -/- mice, which is blocked by NLRP3 and Caspase-8 inhibitors.

bioRxiv · Aug 18, 2022Immunology

Multi-excitation Raman Spectroscopy Complements Whole Genome Sequencing for Rapid Detection of Bacterial Infection and Resistance in WHO Priority Pathogens

A. Lister, E. Avershina, J. Ali, G. Devitt, N. Hanrahan, C. J. Highmore, J. S. Webb, F. Müller, S. Mahajan, R. Ahmad

This paper combines multi-excitation Raman spectroscopy with whole-genome sequencing to rapidly detect bacterial infections and resistance in WHO priority pathogens, achieving high accuracy in classification.

bioRxiv · Feb 8, 2022 · PreprintMicrobiology

Label-free and Multimodal Second Harmonic Generation Light Sheet Microscopy

N. Hanrahan, S. I. R. Lane, P. B. JOHNSON, K. N. Bourdakos, C. J. Brereton, R. A. Ridley, E. R. Davies, N. A. Hosny, G. Spickermann, R. Forster, G. Malcolm, D. E. Davies, M. G. Jones, S. Mahajan

This paper demonstrates a label-free SHG-LSM technique for 3D imaging of collagen and other harmonophores, combining SHG with light sheet microscopy for multimodal imaging.

bioRxiv · Sep 7, 2020 · PreprintBiophysics