Author

D. F. Q. Smith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:ecology & biodiversity· 1 Organism:fungi (other)· 1 Assay:imaging· 1

Frequent Co-Authors

A. Casadevall· 5 shared J. M. Hardwick· 2 shared M. Kulkarni· 2 shared A. Bencomo· 1 shared A. J. Barron· 1 shared B. Smith· 1 shared C. Chrissian· 1 shared D. Zamith-Miranda· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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5 shared papersMicrobiology

A. Casadevall

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Environmental fungi from cool and warm neighborhoods in the urban heat island of Baltimore City show differences in thermal susceptibility and pigmentation

D. F. Q. Smith, M. Kulkarni, A. Bencomo, T. S. Faiez, J. M. Hardwick, A. Casadevall

The paper collects and analyzes fungal isolates from urban neighborhoods in Baltimore, finding that warmer area isolates show greater thermotolerance and lighter pigmentation, suggesting local adaptation to heat.

bioRxiv · Nov 10, 2023 · PreprintMicrobiology

Melanization of Candida auris is Associated with Alteration of Extracellular pH

D. F. Q. Smith, N. J. Mudrak, D. Zamith-Miranda, L. Honorato, L. Nimrichter, C. Chrissian, B. Smith, G. J. Gerfen, R. E. Stark, J. D. Nosanchuk, A. Casadevall

This study identifies a novel mechanism of melanization in C. auris through extracellular alkalinization promoting non-enzymatic oxidation of L-DOPA to melanin.

bioRxiv · Jul 14, 2022Microbiology

Melanization is an important antifungal defense mechanism in Galleria mellonella hosts

D. F. Q. Smith, Q. Dragotakes, M. Kulkarni, J. M. Hardwick, A. Casadevall

This study shows that melanization in Galleria mellonella larvae directly kills Cryptococcus neoformans and Candida albicans by encapsulating fungal cells, with some yeast forms surviving and breaking through encapsulation.

bioRxiv · Apr 2, 2022 · PreprintMicrobiology

On the relationship between Pathogenic Potential and Infective Inoculum

D. F. Q. Smith, A. Casadevall

The paper quantifies the relationship between pathogenic potential and infective inoculum in microbes, finding exponential and linear patterns that reflect differences in host-microbe interactions.

bioRxiv · Mar 31, 2022Microbiology

Glyphosate Inhibits Melanization and Increases Susceptibility to Infection in Insects

D. F. Q. Smith, E. Camacho, R. Thakur, A. J. Barron, Y. Dong, G. Dimopoulos, N. A. Broderick, A. Casadevall

This study shows glyphosate inhibits melanin production in insects, reducing their survival after infection and increasing susceptibility to pathogens.

bioRxiv · May 20, 2020Microbiology