Author

J. M. Hardwick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Research Focus:development & morphogenesis· 1 Approach:microscopy & imaging analysis· 1 Organism:mouse· 1

Frequent Co-Authors

A. Casadevall· 4 shared M. Kulkarni· 4 shared D. F. Q. Smith· 2 shared A. Bencomo· 1 shared A. Jalisi· 1 shared C. Coelho· 1 shared C. Liddle· 1 shared C. Zhu· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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4 shared papersMicrobiology

A. Casadevall

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cryptococcus neoformans rapidly invades the murine brain by sequential breaching of airway and endothelial tissues barriers, followed by engulfment by microglia

V. Francis, C. Liddle, E. Camacho, M. Kulkarni, S. R. Junior, J. A. Harvey, E. R. Ballou, D. D. Thomson, J. M. Hardwick, A. Casadevall, J. Witton, C. Coelho

bioRxiv · Nov 13, 2023Microbiology

Environmental fungi from cool and warm neighborhoods in the urban heat island of Baltimore City show differences in thermal susceptibility and pigmentation

D. F. Q. Smith, M. Kulkarni, A. Bencomo, T. S. Faiez, J. M. Hardwick, A. Casadevall

The paper collects and analyzes fungal isolates from urban neighborhoods in Baltimore, finding that warmer area isolates show greater thermotolerance and lighter pigmentation, suggesting local adaptation to heat.

bioRxiv · Nov 10, 2023 · PreprintMicrobiology

Melanization is an important antifungal defense mechanism in Galleria mellonella hosts

D. F. Q. Smith, Q. Dragotakes, M. Kulkarni, J. M. Hardwick, A. Casadevall

This study shows that melanization in Galleria mellonella larvae directly kills Cryptococcus neoformans and Candida albicans by encapsulating fungal cells, with some yeast forms surviving and breaking through encapsulation.

bioRxiv · Apr 2, 2022 · PreprintMicrobiology

Gene-dependent yeast cell death pathway requires AP-3 vesicle trafficking leading to vacuole membrane permeabilization

Z. D. Stolp, M. Kulkarni, Y. Liu, C. Zhu, A. Jalisi, S. Lin, A. Casadevall, K. W. Cunningham, F. J. Pineda, X. Teng, J. M. Hardwick

The paper identifies an AP-3-dependent pathway in yeast leading to vacuole membrane permeabilization and cell death, conserved in Cryptococcus neoformans.

bioRxiv · Aug 2, 2021 · PreprintCell Biology