Author

J. D. Nosanchuk

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:proteomics· 6 Research Focus:cell type annotation· 5 Organism:fungi (other)· 4 Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Organism:C. elegans· 2 Research Focus:drug response / drug discovery· 2

Frequent Co-Authors

D. Zamith-Miranda· 6 shared L. Nimrichter· 4 shared E. S. Nakayasu· 3 shared H. M. Heyman· 3 shared L. R. Alves· 3 shared S. P. Couvillion· 3 shared A. Casadevall· 2 shared A. Gacser· 2 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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Curved chords = mutual co-authorship

6 shared papersMicrobiology

D. Zamith-Miranda

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Melanization of Candida auris is Associated with Alteration of Extracellular pH

D. F. Q. Smith, N. J. Mudrak, D. Zamith-Miranda, L. Honorato, L. Nimrichter, C. Chrissian, B. Smith, G. J. Gerfen, R. E. Stark, J. D. Nosanchuk, A. Casadevall

This study identifies a novel mechanism of melanization in C. auris through extracellular alkalinization promoting non-enzymatic oxidation of L-DOPA to melanin.

bioRxiv · Jul 14, 2022Microbiology

Replicative Aging Remodels Cell Wall and is Associated with Increased Intracellular Trafficking in Human Pathogenic Yeasts

V. K. A. Silva, S. Bhattacharya, N. K. Oliveira, A. G. Savitt, D. Zamith-Miranda, J. D. Nosanchuk, B. C. Fries

This study shows that replicative aging in Cryptococcus neoformans and Candida glabrata leads to cell wall thickening and increased intracellular trafficking.

bioRxiv · Jan 25, 2022Microbiology

Oral epithelial cells distinguish between Candida species with high or low pathogenic potential through miRNA regulation

M. Horvath, G. Nagy, N. Zsindely, L. Bodai, P. Horvath, C. Vagvolgyi, J. D. Nosanchuk, R. Toth, A. Gacser

The paper shows oral epithelial cells respond differently to C. albicans and C. parapsilosis, with miRNA regulation playing a key role in distinguishing their pathogenic potential.

bioRxiv · Jan 23, 2021 · PreprintMicrobiology

Extracellular vesicles regulate yeast growth, biofilm formation, and yeast-to-hypha differentiation in Candida albicans

L. Honorato, J. F. Demetrio, C. C. Ellis, A. C. Piffer, Y. Pereira, S. Frases, G. Araujo, B. Pontes, M. T. Mendes, M. D. Pereira, A. J. Guimaraes, N. M. da Silva, G. Vargas, L. Joffe, M. Del Poeta, , L. Nimrichter

This study shows that extracellular vesicles from Candida albicans inhibit biofilm formation, yeast-to-hypha differentiation, and virulence by altering gene expression and morphology.

bioRxiv · Jan 21, 2021 · PreprintMicrobiology

Comparative molecular and immunoregulatory analysis of extracellular vesicles from Candida albicans and Candida auris.

D. Zamith-Miranda, H. M. Heyman, S. P. Couvillion, R. J. B. Cordero, M. Rodrigues, L. Nimrichter, A. Casadevall, R. Amatuzzi, L. R. Alves, E. S. Nakayasu, J. D. Nosanchuk

This study compares extracellular vesicles from Candida auris and Candida albicans, finding distinct molecular profiles and immune-modulating properties that may contribute to C. auris pathogenesis.

bioRxiv · Nov 4, 2020Microbiology

A Histoplasma capsulatum lipid metabolic map identifies antifungal targets

D. Zamith-Miranda, H. M. Heyman, M. C. Burnet, S. P. Couvillion, X. Zheng, N. Munoz, W. C. Nelson, J. E. Kyle, E. M. Zink, K. K. Weitz, K. J. Bloodsworth, G. C. Clair, J. D. Zucker, J. R. Teuton, S. H. Payne, , E. S. Nakayasu

This study constructs a lipid metabolic map of Histoplasma capsulatum and identifies potential antifungal drug targets through pathway validation and compound testing.

bioRxiv · Mar 2, 2020Microbiology

Extracellular vesicle-mediated RNA release in Histoplasma capsulatum

L. R. Alves, R. Peres da Silva, D. A. Sanchez, D. Zamith-Miranda, M. L. Rodrigues, S. Goldenberg, R. Puccia, J. D. Nosanchuk

This study identifies strain-specific RNA content in extracellular vesicles from two Histoplasma capsulatum isolates, highlighting strain differences and potential miRNA-like molecules.

bioRxiv · Mar 7, 2019Microbiology

Candida auris: multi-omics signature of an emerging and multidrug-resistant pathogen

D. Zamith-Miranda, H. M. Heyman, L. G. Cleare, S. P. Couvillion, G. C. Clair, E. L. Bredeweg, A. Gacser, L. Nimrichter, E. S. Nakayasu, J. D. Nosanchuk

This paper compares multi-omics profiles of two Candida auris isolates and a Candida albicans reference strain to understand drug resistance and virulence mechanisms.

bioRxiv · Jan 23, 2019Microbiology