Author

D. Francisci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Assay:bulk RNA-seq· 1 Organism:mouse· 1

Frequent Co-Authors

A. Carino· 2 shared A. Zampella· 2 shared B. Catalanotti· 2 shared B. Fiorillo· 2 shared E. Distrutti· 2 shared M. Biagioli· 2 shared S. Fiorucci· 2 shared A. Gidari· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersPharmacology & Toxicology

A. Carino

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2 papers

Recent·Most cited

Discovery of a AhR flavonoid agonist that counter-regulates ACE2 expression in rodent models of inflammation and attenuates ACE2-SARS-CoV2 interaction in vitro

M. Biagioli, S. Marchiano, R. Roselli, C. Di Giorgio, R. Bellini, M. Bordoni, A. Gidari, S. Sabbatini, D. Francisci, B. Fiorillo, B. Catalanotti, E. Distrutti, A. Carino, A. Zampella, G. Costantino, S. Fiorucci

This study identifies pelargonidin, a flavonoid that reduces ACE2 expression and SARS-CoV2 binding in inflamed colons via AhR activation.

bioRxiv · Feb 24, 2021Pharmacology & Toxicology

Hijacking SARS-Cov-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on receptor binding region

A. Carino, F. Moraca, B. Fiorillo, S. Marcano, V. Sepe, M. Biagioli, C. Finamore, S. Bozza, D. Francisci, E. Distrutti, B. Catalanotti, A. Zampella, S. Fiorucci

This study identifies steroidal agents that inhibit SARS-CoV-2 entry by targeting binding pockets on the Spike protein's receptor-binding domain.

bioRxiv · Jun 10, 2020Pharmacology & Toxicology