Author

B. Catalanotti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Assay:metabolomics· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Zampella· 4 shared E. Distrutti· 4 shared M. Biagioli· 4 shared S. Fiorucci· 4 shared B. Fiorillo· 3 shared C. Di Giorgio· 3 shared M. Bordoni· 3 shared R. Bellini· 3 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersPharmacology & Toxicology

A. Zampella

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Author profile →

4 papers

Recent·Most cited

A microbial derived bile acid acts as GPBAR1 agonist and RORγt inverse agonist and reverses inflammation in inflammatory bowel disease

M. Biagioli, C. Di Giorgio, C. Massa, S. Marchiano', R. Bellini, M. Bordoni, G. Urbani, R. Roselli, G. Lachi, E. Morretta, F. Dal Piaz, B. Charlier, B. Fiorillo, B. Catalanotti, L. Cari, , S. Fiorucci

This study identifies 3-oxo-DCA as a microbial bile acid that acts as a GPBAR1 agonist and RORγt inverse agonist, reversing inflammation in IBD.

bioRxiv · Apr 8, 2024 · PreprintImmunology

Bile Acids Serve As Endogenous Antagonists Of The Leukemia Inhibitory Factor (LIF) Receptor in Oncogenesis

C. Di Giorgio, E. Morretta, A. Lupia, R. Bellini, C. Massa, G. Urbani, M. Bordoni, S. Marchiano, P. Rapacciuolo, C. Finamore, V. Sepe, M. C. Monti, F. Monarca, N. Natalizi, L. Graziosi, , S. Fiorucci

The paper shows bile acids, specifically GDCA, inhibit LIFR in gastric cancer, suggesting potential for bile acid-based therapies in LIF-driven oncogenesis.

bioRxiv · Sep 30, 2023Cancer Biology

Discovery of a AhR flavonoid agonist that counter-regulates ACE2 expression in rodent models of inflammation and attenuates ACE2-SARS-CoV2 interaction in vitro

M. Biagioli, S. Marchiano, R. Roselli, C. Di Giorgio, R. Bellini, M. Bordoni, A. Gidari, S. Sabbatini, D. Francisci, B. Fiorillo, B. Catalanotti, E. Distrutti, A. Carino, A. Zampella, G. Costantino, S. Fiorucci

This study identifies pelargonidin, a flavonoid that reduces ACE2 expression and SARS-CoV2 binding in inflamed colons via AhR activation.

bioRxiv · Feb 24, 2021Pharmacology & Toxicology

Hijacking SARS-Cov-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on receptor binding region

A. Carino, F. Moraca, B. Fiorillo, S. Marcano, V. Sepe, M. Biagioli, C. Finamore, S. Bozza, D. Francisci, E. Distrutti, B. Catalanotti, A. Zampella, S. Fiorucci

This study identifies steroidal agents that inhibit SARS-CoV-2 entry by targeting binding pockets on the Spike protein's receptor-binding domain.

bioRxiv · Jun 10, 2020Pharmacology & Toxicology