Author

D. G. Schatz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:DNA methylation· 4 Approach:experimental assay· 4 Research Focus:chromatin & epigenetic regulation· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Research Focus:gene regulatory network inference· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

F. Senigl· 2 shared J. Alinikula· 2 shared A. I. Soikkeli· 1 shared A. Soikkeli· 1 shared A. Tarsalainen· 1 shared A.-J. Petrescu· 1 shared C.-Y. Lin· 1 shared D. Baltimore· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

F. Senigl

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The SV40 virus enhancer functions as a somatic hypermutation-targeting element with potential oncogenic activity

F. Senigl, A. I. Soikkeli, S. Prost, D. G. Schatz, M. Slavkova, J. Hejnar, J. Alinikula

This study shows the SV40 enhancer targets somatic hypermutation, leading to LT truncation and potential oncogenic activity in B and kidney cells.

bioRxiv · Jan 9, 2024 · PreprintMicrobiology

Insights into RAG evolution from the identification of "missing link" family A RAGL transposons

E. C. Martin, L. Le Targa, L. Tsakou-Ngouafo, T.-P. Fan, C.-Y. Lin, J. Xiao, Y.-H. Su, A.-J. Petrescu, P. Pontarotti, D. G. Schatz

The paper identifies RAGL-A transposons in invertebrates, showing they share features with both RAG and RAGL-B, suggesting they are a critical intermediate in RAG evolution.

bioRxiv · Aug 20, 2023 · PreprintEvolutionary Biology

Immunoglobulin enhancers increase RNA polymerase stalling at somatic hypermutation target sequences

A. Tarsalainen, Y. Maman, F.-L. Meng, M. K. Kylaniemi, A. Soikkeli, P. Budzynska, J. J. McDonald, F. Senigl, F. W. Alt, D. G. Schatz, J. Alinikula

The paper shows that immunoglobulin enhancers (DIVACs) increase RNA polymerase stalling at somatic hypermutation target sequences in B cells.

bioRxiv · Sep 16, 2021Immunology

Sequence-Dependent Dynamics of Synthetic and Endogenous RSSs in V(D)J Recombination

S. Hirokawa, G. Chure, N. M. Belliveau, G. A. Lovely, M. Anaya, D. G. Schatz, D. Baltimore, R. Phillips

The paper quantifies sequence-dependent dynamics of RAG-RSS interactions in V(D)J recombination, revealing how single-bp changes affect PC formation, stability, and cleavage.

bioRxiv · Oct 4, 2019Immunology