Inhibition of the YAP-MMB interaction and targeting NEK2 as potential therapeutic strategies for YAP-driven cancers
M. Jessen, D. Gertzmann, F. Liss, F. Zenk, L. Baehner, V. Schoeffler, C. P. Ade, B. von Eyss, S. Gaubatz
This study identifies disrupting YAP-B-MYB interaction and targeting NEK2 as potential therapies for YAP-driven cancers, showing reduced tumorigenesis and cell cycle defects.
bioRxiv · Jul 27, 2023Cancer Biology