Author

D. H. Perlman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:protein folding & dynamics· 2 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. A. Petelski· 2 shared A. Leduc· 2 shared E. Emmott· 2 shared H. Specht· 2 shared N. Slavov· 2 shared R. G. Huffman· 2 shared A. Goedecke· 1 shared A. I. Casas· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

A. A. Petelski

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Prioritized single-cell proteomics reveals molecular and functional polarization across primary macrophages

R. G. Huffman, A. Leduc, C. Wichmann, M. di Gioia, F. Borriello, H. Specht, J. Derks, S. Khan, L. Khoury, E. Emmott, A. A. Petelski, D. H. Perlman, J. Cox, I. Zanoni, N. Slavov

The paper introduces pSCoPE, a single-cell proteomics method that improves sensitivity, completeness, and depth, enabling analysis of protein variation in macrophages.

bioRxiv · Mar 16, 2022Immunology

Detection of Cell-Cell Interactions via Photocatalytic Cell Tagging

R. C. Oslund, T. Reyes-Robles, C. H. White, J. H. Tomlinson, K. A. Crotty, E. P. Bowman, D. Chang, V. M. Peterson, L. Li, S. Frutos, M. Vila-Perello, D. Vlerick, K. Cromie, D. H. Perlman, S. D. O'Hara, , O. O. Fadeyi

This paper introduces PhoTag, a method to detect cell-cell interactions by labeling cell surfaces with photocatalytic tags, enabling analysis of gene expression differences between interacting and bystander cells.

bioRxiv · Oct 4, 2021Immunology

Multiplexed single-cell proteomics using SCoPE2

A. A. Petelski, E. Emmott, A. Leduc, R. G. Huffman, H. Specht, D. H. Perlman, N. Slavov

The paper introduces SCoPE2, a multiplexed single-cell proteomics method that enables quantitative analysis of over 1,000 proteins per cell using standard equipment.

bioRxiv · Mar 12, 2021Bioengineering

Nitrative signaling into cardiac lactate dehydrogenase Trp324 modulates active site loop mobility and activity under metabolic stress

C. Nogales, J. Frihoff, D. Thoenges, R. B. Sessions, A. Sickmann, T. Nedvetskaya, C. Ibarra-Alvarado, V. Schmitz, P. Rosen, A. Goedecke, A. Jovanovic, D. H. Perlman, A. Klinke, S. Baldus, A. I. Casas, , H. H. H. W. Schmidt

This study identifies Trp324 nitration in lactate dehydrogenase as a physiological signaling mechanism modulating enzyme activity under metabolic stress.

bioRxiv · Jan 15, 2019 · PreprintBiochemistry