C. H. White

Proteomic Mapping of Intercellular Synaptic Environments via Flavin-Dependent Photoredox Catalysis

The paper uses photocatalytic labeling and proteomics to map protein microenvironments in immune synapses, identifying known and novel proteins involved in T cell-antigen-presenting cell interactions.

High resolution photocatalytic mapping of SARS-CoV-2 Spike protein-host cell membrane interactions

This study identifies additional host proteins involved in SARS-CoV-2 entry using a novel photocatalytic mapping platform called ViraMap.

Placental uptake and metabolism of 25(OH)Vitamin D determines its activity within the fetoplacental unit

This study shows the human placenta actively transports and metabolizes 25(OH)D3 into active vitamin D metabolites, influencing fetal development through placental transcriptome and proteome changes.

Novel neutrophil subsets associated with sepsis, vascular dysfunction and metabolic alterations identified using systems immunology

The paper identifies novel neutrophil subsets in sepsis patients using systems immunology and links them to cytokines, metabolites, and lipids, enabling a predictive model for patient classification.

Detection of Cell-Cell Interactions via Photocatalytic Cell Tagging

This paper introduces PhoTag, a method to detect cell-cell interactions by labeling cell surfaces with photocatalytic tags, enabling analysis of gene expression differences between interacting and bystander cells.

Vaccine Hyporesponse Induced By Individual Antibiotic Treatment In Mice And Non-Human Primates Is Diminished Upon Recovery Of The Gut Microbiome

This study shows that antibiotic-induced gut microbiome disruption reduces vaccine response in mice and non-human primates, but recovery of microbiome diversity restores immune responses.