Author

D. J. Stephens

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:development & morphogenesis· 3 Research Focus:chromatin & epigenetic regulation· 2 Organism:human· 2 Assay:proteomics· 2 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

K. Heesom· 2 shared L. Vuolo· 2 shared N. L. Stevenson· 2 shared A. G. Mukhopadhyay· 1 shared A. J. Roberts· 1 shared A. Paterson· 1 shared A. Pugnetti· 1 shared C. L. Hammond· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersCell Biology

K. Heesom

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Author profile →

4 papers

Recent·Most cited

Roles for CEP170 in cilia function and dynein-2 assembly.

J. F. Weijman, L. Vuolo, C. Shak, A. Pugnetti, A. G. Mukhopadhyay, L. R. Hodgson, K. J. Heesom, A. J. Roberts, D. J. Stephens

This study identifies CEP170 as a protein interacting with dynein-2, showing its role in dynein-2 assembly and cilia function through effects on intraflagellar transport and Hedgehog signaling.

bioRxiv · Nov 20, 2023Cell Biology

A general role for MIA3/TANGO1 in secretory pathway organization and function.

J. McCaughey, N. L. Stevenson, J. M. Mantell, C. R. Neal, A. Paterson, K. Heesom, D. J. Stephens

The paper shows that TANGO1L and TANGO1S are essential for secretory pathway structure and function, with loss of both causing major defects in secretion and ER-Golgi organization.

bioRxiv · Feb 24, 2021 · PreprintCell Biology

Giantin is required for intracellular N-terminal processing of type I procollagen

N. Stevenson, D. Bergen, C. L. Hammond, D. J. Stephens

This study shows that giantin is essential for intracellular N-terminal processing of type I procollagen, affecting bone mineralization and leading to skeletal defects in zebrafish.

bioRxiv · May 25, 2020Cell Biology

Dynein-2 intermediate chains play crucial but distinct roles in primary cilia formation and function

L. Vuolo, N. L. Stevenson, K. Heesom, D. J. Stephens

This study identifies distinct roles of dynein-2 intermediate chains WDR34 and WDR60 in cilia formation and function using knockout cell lines.

bioRxiv · Feb 1, 2018Cell Biology