BiochemistrybioRxivPreprint
Phage display uncovers a sequence motif that drives polypeptide binding to a conserved regulatory exosite of O-GlcNAc transferase
M. G. Alteen, R. W. Meek, S. Kolappan…·D. J. Vocadlo
The paper identifies a peptide sequence motif that binds to OGT's exosite, causing allosteric inhibition through steric occlusion of the active site.
DOI 10.1101/2023.03.15.532872