Discovery of a celecoxib binding site on PTGES with a cleavable chelation-assisted biotin probe
D. K. Miyamoto, H. A. Flaxman, H.-Y. Wu, J. Gao, C. M. Woo
This paper identifies a new celecoxib binding site on PTGES using a cleavable chelation-assisted biotin probe and validates it through competitive displacement and structural modeling.
bioRxiv · Sep 26, 2019Pharmacology & Toxicology