Therapeutic downregulation of neuronal PAS domain 2 (Npas2) promotes surgical skin wound healing
Y. Shibuya, A. Hokugo, H. Okawa, T. Kondo, D. Khalil, L. Wang, Y. Roca, A. Clements, H. Sasaki, E. Berry, I. Nishimura, R. Jarrahy
This study identifies a compound, Dwn1, that downregulates Npas2 and accelerates wound healing with reduced scarring in mice.
bioRxiv · Nov 29, 2021Bioengineering