Y-RNA and tRNA Cleavage by RNase L Mediates Terminal dsRNA Response
J. Donovan, S. Rath, D. Kolet-Mandrikov, A. Korennykh
The paper identifies RNase L as the enzyme responsible for cleaving Y-RNAs and tRNAs in response to dsRNA, with RNY1 depletion initiating apoptosis.
bioRxiv · Nov 10, 2016Immunology