Genetically Targeted Ratiometric and Activated pH Indicator Complexes (TRApHIC) for Receptor Trafficking
L. A. Perkins, Q. Yan, B. F. Schmidt, D. Kolodiezyni, S. Saurabh, M. B. Larsen, S. C. Watkins, L. Kremer, M. P. Bruchez
The paper develops TRApHIC, a genetically targeted pH sensor for studying receptor trafficking, revealing agonist-specific differences in B2AR endocytosis and recycling.
bioRxiv · Aug 24, 2017Cell Biology