Author

S. Saurabh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Approach:deep learning· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

B. F. Schmidt· 1 shared C. Bayas· 1 shared D. Kolodiezyni· 1 shared F. Piazza· 1 shared H. N. Cartwright· 1 shared L. A. Perkins· 1 shared L. Kremer· 1 shared L. Shapiro· 1 shared

Activity by Year

2017-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperCell Biology

B. F. Schmidt

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ATP-responsive biomolecular condensates tune bacterial kinase signaling

S. Saurabh, T. N. Chong, C. Bayas, P. D. Dahlberg, H. N. Cartwright, W. E. Moerner, L. Shapiro

The paper shows ATP depletion enhances kinase activity via phase separation in bacterial condensates, enabling robust signaling under nutrient stress.

bioRxiv · Aug 9, 2020Microbiology

A modified ACE2 peptide mimic to block SARS-CoV2 entry

S. Saurabh, S. S. Purohit

The paper analyzes a modified ACE2 peptide mimic to block SARS-CoV2 entry by studying its binding energetics and demonstrating improved binding through point mutations.

bioRxiv · May 7, 2020 · PreprintBiophysics

Mesoscale computational protocols for the design of highly cooperative bivalent macromolecules

S. Saurabh, F. Piazza

This paper develops mesoscale computational protocols to design bivalent macromolecules with optimized binding cooperativity using coarse-grained models and statistical mechanics.

bioRxiv · Aug 21, 2019Biophysics

Genetically Targeted Ratiometric and Activated pH Indicator Complexes (TRApHIC) for Receptor Trafficking

L. A. Perkins, Q. Yan, B. F. Schmidt, D. Kolodiezyni, S. Saurabh, M. B. Larsen, S. C. Watkins, L. Kremer, M. P. Bruchez

The paper develops TRApHIC, a genetically targeted pH sensor for studying receptor trafficking, revealing agonist-specific differences in B2AR endocytosis and recycling.

bioRxiv · Aug 24, 2017Cell Biology