Author

M. B. Larsen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

B. B. Chen· 2 shared A. Ahner· 1 shared B. F. Schmidt· 1 shared B. Van Houten· 1 shared B. Wang· 1 shared B. Zhu· 1 shared C. Bertrand· 1 shared C. DuPont· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

B. B. Chen

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Author profile →

4 papers

Recent·Most cited

SON-dependent nuclear speckle rejuvenation alleviates proteinopathies

W. Dion, Y. Tao, M. Chambers, S. Zhao, R. K. Arbuckle, M. Sun, S. Kubra, M. Schaich, Y. Nie, M. Ye, I. Jamal, M. B. Larsen, D. Camarco, E. Ickes, H. Wang, , B. Zhu

This study identifies pyrvinium pamoate as a compound that rejuvenates nuclear speckles, improving protein quality control and reducing YAP1 activity, thereby alleviating proteinopathies in pre-clinical models.

bioRxiv · Apr 18, 2024Cell Biology

Discovery of bactericides as an acute mitochondrial membrane damage inducer

R. Houston, Y. Sekine, M. B. Larsen, K. Murakami, D. P. Narendra, B. B. Chen, S. Sekine

The paper identifies Chlorhexidine and Alexidine as bactericides that induce acute mitochondrial membrane damage by altering inner mitochondrial membrane integrity and evoking a unique stress response.

bioRxiv · Apr 9, 2021Cell Biology

Different SUMO Paralogs Determine the Fate of WT and Mutant CFTRs: Biogenesis vs. Degradation

X. Gong, Y. Liao, A. Ahner, M. B. Larsen, X. Wang, C. Bertrand, R. A. Frizzell

This study shows that SUMO paralogs determine the fate of WT and mutant CFTRs, with PIAS4 promoting biogenesis and reducing degradation.

bioRxiv · Jun 7, 2018Cell Biology

Genetically Targeted Ratiometric and Activated pH Indicator Complexes (TRApHIC) for Receptor Trafficking

L. A. Perkins, Q. Yan, B. F. Schmidt, D. Kolodiezyni, S. Saurabh, M. B. Larsen, S. C. Watkins, L. Kremer, M. P. Bruchez

The paper develops TRApHIC, a genetically targeted pH sensor for studying receptor trafficking, revealing agonist-specific differences in B2AR endocytosis and recycling.

bioRxiv · Aug 24, 2017Cell Biology