Author

D. Kukla

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

S. Khetani· 2 shared A. Crampton· 1 shared D. Kaplan· 1 shared D. Wood· 1 shared W. Stoppel· 1 shared

Activity by Year

2019-2020 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 6 mutual co-author links

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2 shared papersBioengineering

S. Khetani

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Primary Human Hepatocytes Maintain Long-term Functions in Porous Silk Scaffolds Containing Extracellular Matrix Proteins

D. Kukla, W. Stoppel, D. Kaplan, S. Khetani

This study shows that porous silk scaffolds with collagen and fibroblasts support long-term function of primary human hepatocytes, up to 5 months in culture.

bioRxiv · Jan 30, 2020 · PreprintBioengineering

Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in 3-Dimensional Models

D. Kukla, A. Crampton, D. Wood, S. Khetani

This study develops 3D collagen microtissues with fibroblast coatings to sustain primary human hepatocyte functions for 6+ weeks, outperforming spheroids and macrogels in hepatic function and drug response.

bioRxiv · Nov 29, 2019Bioengineering