Author

A. Crampton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. Wood· 2 shared A. Kinne· 1 shared A. Ray· 1 shared D. DeNardo· 1 shared D. Kukla· 1 shared E. Ensminger· 1 shared H. Jiang· 1 shared H. Rasmussen· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersCancer Biology

D. Wood

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Stromal architecture directs early dissemination in pancreatic ductal adenocarcinoma

A. Ray, M. Callaway, N. Rodriguez-Merced, A. Crampton, M. Carlson, K. Emme, E. Ensminger, A. Kinne, J. Schrope, H. Rasmussen, H. Jiang, D. DeNardo, D. Wood, P. Provenzano

This study shows that stromal collagen structures in pancreatic ductal adenocarcinoma promote early dissemination from pre-malignant lesions and ongoing invasion, suggesting FAK inhibition or stroma normalization could limit metastasis.

bioRxiv · Feb 19, 2021Cancer Biology

Microscale Collagen and Fibroblast Interactions Enhance Primary Human Hepatocyte Functions in 3-Dimensional Models

D. Kukla, A. Crampton, D. Wood, S. Khetani

This study develops 3D collagen microtissues with fibroblast coatings to sustain primary human hepatocyte functions for 6+ weeks, outperforming spheroids and macrogels in hepatic function and drug response.

bioRxiv · Nov 29, 2019Bioengineering