Enzymatic and structural characterization of HAD5, an essential phosphomannomutase of malaria parasites
P. M. Frasse, J. J. Miller, E. Soleimani, J.-S. Zhu, D. L. Jakeman, J. M. Jez, D. E. Goldberg, A. R. Odom John
This study characterizes HAD5, a phosphomannomutase essential for GPI anchor biosynthesis in malaria parasites, showing its role in parasite egress and reinvasion and identifying a specific inhibitor.
bioRxiv · Jul 3, 2021Microbiology