In the absence of apoptosis, myeloid cells arrest when deprived of growth factor, but remain viable by consuming extracellular glucose
L. Dong, B. Reljic, J. G. Cheung, E. S. Ng, L. M. Lindqvist, A. G. Elefanty, D. L. Vaux, H. Tran
The paper shows that Bax-/-Bak1-/- myeloid cells deprived of IL3 survive by consuming extracellular glucose, without needing Atg5-dependent autophagy.
bioRxiv · Nov 15, 2018Cell Biology