Author

D. N. Rupani

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

A. D. Rhim· 1 shared A. Maitra· 1 shared B. B. Bharati· 1 shared F. I. Thege· 1 shared S. L. Manning· 1 shared S. M. Woermann· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

A. D. Rhim

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1 paper

Recent·Most cited

Programmable in vivo CRISPR activation elucidates the oncogenic and immunosuppressive role of MYC in lung adenocarcinoma

F. I. Thege, D. N. Rupani, B. B. Bharati, S. L. Manning, A. Maitra, A. D. Rhim, S. M. Woermann

This study uses CRISPR activation to show MYC promotes lung cancer growth and creates an immunosuppressive tumor environment, suggesting combined MYC/immune therapies could benefit patients.

bioRxiv · Dec 9, 2021 · PreprintCancer Biology