Author

S. M. Woermann

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Maitra· 2 shared A. A. Singhi· 1 shared A. D. Rhim· 1 shared A. N. Hosein· 1 shared B. B. Bharati· 1 shared B. Ghosh· 1 shared C. L. Haymaker· 1 shared D. N. Rupani· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersCancer Biology

A. Maitra

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2 papers

Recent·Most cited

Programmable in vivo CRISPR activation elucidates the oncogenic and immunosuppressive role of MYC in lung adenocarcinoma

F. I. Thege, D. N. Rupani, B. B. Bharati, S. L. Manning, A. Maitra, A. D. Rhim, S. M. Woermann

This study uses CRISPR activation to show MYC promotes lung cancer growth and creates an immunosuppressive tumor environment, suggesting combined MYC/immune therapies could benefit patients.

bioRxiv · Dec 9, 2021 · PreprintCancer Biology

Loss of Rnf43 accelerates Kras-mediated neoplasia and remodels the tumor immune microenvironment in pancreatic adenocarcinoma

A. N. Hosein, G. Dangol, T. Okumura, J. Roszik, K. Rajapakshe, M. Siemann, B. Ghosh, M. E. Monberg, P. A. Guerrero, M. Zaid, A. A. Singhi, C. L. Haymaker, H. Clevers, S. M. Woermann, L. Abou-Elkacem, A. Maitra

This study shows that loss of Rnf43 accelerates Kras-driven pancreatic cancer and alters the tumor immune microenvironment by increasing lymphocytes and immune checkpoint expression.

bioRxiv · May 29, 2021Cancer Biology